IS IT SUFFICIENT TO MEASURE THE BRACHIAL BP ALONE?
As seen from the diagram below, two persons can have exactly the same brachial BP (125/80), but different CASP (105 vs 120 mmHg). It is important to know the CASP as it has been shown in recent studies to be the strongest independent indicator for strokes, heart disease and their survival rate.


More importantly, different drugs can have different and varying effects on the CASP even as they lower the brachial pressure*. As a result, some medications may be detrimental to the patient even as the brachia! BP is being lowered.


The reason for not measuring the CASP widely is mainly due to the fact that, to date, there is no device accurate, affordable and simple enough to be used in a clinic or hospital setting.
The present technique is either an invasive angiographic measurement, or using very expensive and cumbersome systems which is only used in research labs.
With A-PULSE CASPro®, we can do this conveniently.
(*) Williams B, Lacy P. Central aortic pressure and clinical outcomes. J Hypertens 2009; 27: 1123-1125.

CASPRO

A-PULSE CASPro® is a hospital setting stand alone, all-in-one device for the measurement of Central Aortic Systolic Pressure (CASP) in a clinic or hospital setting.
It is empowered by EVBP technology; a FDA listed and patented technology using modified applanation tonometry on the radial artery at the position of the wrist. It is completely non-invasive, convenient and easy-to-operate.


WHAT IS BLOOD PRESSURE?
Blood Pressure (BP) is the pressure exerted by blood on the wall of an artery. It varies within each heart beat and from beat to beat. The highest pressure is called systolic pressure and the lowest pressure is called diastolic pressure. Blood pressure is usually measured in millimeters of mercury (mmHg) and is represented as systolic / diastolic, for example, 120/80 mmHg.


WHAT IS CASP?
Central Aortic Systolic Pressure (CASP) is the pressure at the root of the Aorta, the largest artery of the body as it emerges from the heart (see diagram).
The CASP is usually lower than brachial pressure (the blood pressure measured at the arm). This difference can be as much as 30 mmHg in young healthy adults but approximates that of the brachial pressure when one gets older. It also becomes closer to the brachial pressure when one is suffering from conditions like Hypertension, uncontrolled Diabetes Mellitus, etc.

KEY FEATURES

  • Complete – no software installation required, no additional PC or laptop needed
  • Built-in calibrator
  • Real-time arterial waveforms
  • Displays patients’ result in the range of normality according to the age
  • Memory storage for up to 200 readings
  • Colour LCD digital display

THE CASP NORMAL REFERENCE RANGE

The normal value of CASP is different for each person, depending on their age and gender. The CASP is considered normal when the pressure is within the two red lines.

HOW CAN WE USE A-PULSE CASPro ?
It can be used in:

  • Screening of patient's vascular status
  • As a follow-up monitor after treatment has been initiated
  • The change in CASP and morphology of waveforms can be compared for assessment
  • Clinical trials – The technology has already been used many global drug trials
  • Research and development